The metabolic and molecular regulation of physical activity and nutrition in skeletal muscle, in relation to ageing

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Professor Philip J Atherton; Chair of Clinical, Metabolic & Molecular Physiology

Professor Philip J Atherton was awarded a BSc (1st class) in 2002, and PhD in 2005 on the subject of skeletal muscle molecular signalling networks. Following a postdoc at the University of Nottingham UK, on a BBSRC grant (molecular mechanisms of age-related sarcopenia), he was awarded a personal Research Councils UK fellowship in Molecular Physiology, where he studied responses of muscle to nutrition and exercise as a function of age. Thereafter (2012), Prof Atherton was promoted to Associate Professor and then to full Professor (2017), both at the University of Nottingham.

Professor Atherton has been PI/Co-I on successful grants >£10M from UK research councils (MRC, BBSRC), charities (e.g. DMT), industry (pharma/nutritional) and EU sources. He has published >160 non-abstract peer-reviewed articles (H-index 58 (Google Scholar), with >15,000 citations (rate >2500/year), an i10 index of 110, and 7 invited book(s) chapters. He is also Editor of American Journal of Physiology – Endocrinology & Metabolism, and Senior Editor for Experimental Physiology, Nutrients, and Applied Physiology, Nutrition & Metabolism, overseeing a lab hosting 4 technicians, ~20 clinical/non-clinical research students & 3 postdocs. The team is based at Derby postgraduate entry medical school under the auspices of a UK MRC/Versus Arthritis Centre of Excellence for Musculoskeletal ageing research (CMAR) and Nottingham’s National institute for health (NIHR) Biomedical Research Centre.

The direction of his work involves the combining of clinical physiology with the application of stable isotope tracers, OMICs, and in vivo/vitro molecular biology - to discover predictors of, the mechanistic basis for, and means to mitigate musculoskeletal declines in age and disease(s).